The explosion was reported in the Princes Restaurant in the Sundes Street, at least 16 people have been killed.
The US military said a number of service members were killed Wednesday in the explosion while conducting a routine patrol in Syria — the first instance of US casualties since President Donald Trump announced his intention to withdraw troops from the country last month.
ISIS claimed responsibility for the rare morning attack in the US-patrolled town of Manbij in northern Syria, saying one of its members carried out a suicide attack and detonated his vest filled with explosives.
Videos released by local activists and news agencies showed a restaurant that suffered extensive damage and a street covered with debris and blood. Several cars were also damaged. Another video showed a helicopter flying over the area.
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